Study of features of activation of compensatory-adaptive mechanisms in the liver of an adult rat in response to subdiaphragmatic vagotomy at the initial stage

Author: Tornike Gogolauri
Keywords: white rat, liver, Subdiaphragmatic vagotomy, polyploidy.
Annotation:

The peculiarities of the compensatory-adaptive processes activation in the liver of the adult rats at subdiaphragmatic vagotomy were studied. In particular, it was shown on the experimental model of subdiaphragmatic vagotomy that the liver adaptation at early stage under the conditions of increased functional load without weight loss is achieved due to the genome growth mechanism activation. In particular, in response to the increased functional load during subdiaphragmatic vagotomy the endoreplication mechanism in the adult rat liver is activated and, as a consequence, a population of highly ploidy G2-0 cells is formed. Studies have shown that during subdiaphragmatic vagotomy the liver responds to the increased functional load without initial mass loss by increasing the genome by activating endoreplication mechanisms and increasing the number of high-ploidy cells.

Lecture files:

საბაკალავრო ნაშრომი [ka]